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The Murdoch Children’s Research Institute in Australia is helping scientists use medicine with stem cells and artificial intelligence to develop precision therapies for pediatric heart disease, the main cause of death and disability in children.
Around 260,000 children heart Around the world every year. In the United States, a child was born with a heart defect every 15 minutes.
“We are really interested in understanding how children develop heart disease and where we can interfere to prevent it from progressing,” said Murdoch Childoch Children’s Institute (MCRI), David Elliott.
Dame Elisabeth Murdoch, the mother of Fox News, Rupert Murdoch, helped find the MCRI of Australia. The Institute is associating with the Gladstone institutes in San Francisco for the Decoding Broken Hearts program.
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Amelia and Elijah Mallinson are two children who could benefit from this research. The brothers live In Melbourne and have the same genetic heart condition.
“We took her to our local emergency because she woke up, she was swollen,” said Amelia’s mother and Elijah, Ebony Mallison. “We thought I was only sleepy, but it turns out that I was entering and leaving consciousness.”
Amelia was two years old when doctors discovered their condition.
Ebony Mallison, center, sits with their two children, Amelia and Elijah, who live with the same genetic heart condition. Its two cases are registered in the broken heart decoder program. (Fox News)
“After having made a chest radiography, they realized that their heart was much larger than it should have been, and realized that it was in heart failure,” Mallison said.
Amelia waited almost a year a heart transplant. After a successful treatment, she lives a life mostly normal. His brother Elijah’s condition was discovered during a caution check.
“It was a great shock because we were not aware of anything that would also have a heart condition. It was a great review to completely rule out that there is nothing wrong,” Mallison said. “I feel that was a little more scary because we could anticipate the bad. But it has been really stable and really healthy so far, it has not yet needed any treatment or therapies, which is great.”
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Elliott said the goal is find diagnoses and treatments Before children like Elijah need a transplant.
The leader of the Group of Heart Diseases, David Elliott, of the Murdoch Children’s Research Institute, examines an image of a heart on his monitor. (Fox News)
“For many, the disease would be absolutely critical if it could correct the problem in the uterus,” Elliott said. “Those who have a very severe heart disease will need three surgeries before they are five years old. And it is very exhausting for the families involved. And so, what we really like to do is really progress and allow these children a much more effective life.”
MCRI is part of the Royal Children’s Hospital, which is about 700 heart conditions every year. Each case is registered in the Decoding Broken Hearts program.
“We can use a special technology called reprogramming. So we take a small sample of this child’s blood,” said Elliott. “From that, we can create a heart cell. And in that heart cell there is an exact replica here in the laboratory of the child’s heart cell.”
Then, researchers create additional small cardiac replicas to alter the function and find possible treatments for Royal Children’s patients.
Scientists use patient blood samples to create small cardiac replicas to study, helped by artificial intelligence. (Fox News)
“We are trying to use all these different tools and technologies to understand how the disease develops and where we can look for new therapies using precision medications to help children heart disease“Elliott said.
One of the newest tools with the help of Gladstone institutes is artificial intelligence.
“Gladstone brings the experience and computational knowledge that is built around the Bay area to use AI to study the disease,” Elliott said. “What allows us to do is millions and millions of experiments on the computer before we bring them to the cell, and that really allows us to attack and look at the ideal place to interfere, to help cure the disease.”
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Amelia and Elijah have also participated in studies to advance even more in conditions of conditions such as yours.
“If you even help a family, it is worth it,” Mallinson said. “Each personnel member with whom he comes into contact in the hospital and investigating, everyone makes a big difference in the lives of children and all in the families of these children.”
If you want to donate or get more information about the Decoding Broken Hearts program, you can visit Go.fox/mcri.