Forgiveness in your blood can give a surprising health benefit

Your constant blood donation can be done good for your own health. The researchers found early evidence of useful changes in cells that increase the blood supply blood donation.

In the Francis Crick Institute and others conducted research, published In the blood magazine on Tuesday. Often the donors have identified genetic mutations in stem cells, which can improve blood cells, which can improve blood loss in the body, but without increasing blood-mutations, but the risk of blood cancer like leukemia. Findings can help scientists understand these cancers better, although the donations are needed to know more of research to know that such conditions are protected from developing such conditions.

Showed plenty of research Significant public health value Blood grant next to you, as well as General security Procedure for potential donors. However, in the opinion of researchers, how often comes the health of the donors, especially when it comes to hematopoetic stem cells, how the cells can affect all types of blood cells. Thus, 200-year-olds have often decided to analyze the collected HSCs – forgive more than 100 times and forgive HABS (a control group) forgiveness of the life.

When HSCS is grown, sometimes blood cells will develop a separate population from other blood cells. This phenomenon is called clonal hematopoiesis (CH) and populations are called clones. As much as we live as is chir more, but usually harmless. Rarely, clones carry them mutations that are tending to be cancer.

Researchers often found that blood donors were to develop the sporadic donors. However, when approaching, they often saw the mutations from donors, especially in a gentleman, in a GEN “in DNMT3A (a common area of ​​general genetic change in CH).

More experiments with crisp edited human HSCs and mice often suggested that the changes related to DNMT3A, which are often seen in donors. The changes appeared to increase the ability to restore new red blood cells in a stressful environment that imitates bloodshed. They did not grow in the conditions that imitate the inflammation (risk factor for cancer growth), on the contrary, it was true for HSCs that made the risk of leukemia.

In general, researchers assume that the blood donation can provide a healthy exercise to our blood-rooted cells, and even cancer be more sustainable.

“Our work is an interesting example of how genes interacts and older,” he said. statement from the institute. “Activities that put a low level of stress on blood cell production allow our blood-rooted cells, and we think it is mutations that encourage root cells than the disease.”

Bonnet and his team notes that it is not clear whether this revealed mutations are really prevented from cancer. The team needs more research and research, which has greater sample dimensions to reach the question of this question. “Now, we are aiming to work in the development or lack of the types of different mutations, and however, we cannot target the role and cannot be targeted,” he said.

However, at least, researchers often found anything that any capacity belongs to the blood donor. If the work is finally brought to a real cancer in practice, if you can, if you can be able to do a long list of potential reasons for your blood donation. Along with the life-saving gift you give to others, blood granules are associated with lower risk heart attackfor example.