This blood vessel grew up in a laboratory with real human cells

About each year Consists of 185,000 people in the United States amputation. About half of them are related to blood vessels in connection with blood vessels. Surgeons can make a whole vascular transplant from another place in the body of a patient to prevent amputation, but there is no suitable vascular for the product of everyone.

A new progress tissue engineering can help. In December, the Food and Drug Department confirmed Bioengineed blood vessel to treat the vein trauma. The North Carolina is designed to restore blood flow in patients, developed by Biotech Company Humacyte, from weapons, car accidents, industrial accidents or battles, such as traumatic injuries.

“Some patients do not have any vein that are very badly injured,” said Laura Niklason, founder and Humacyte CEO. When a patient is the use of a patient, such a vein is often a good substitute for a vein. “Your veins are very thin. It’s weak small structures and your veins are very strong,” he says.

Niklason first interested in the increase in the blood vessels in the 1990s, while Massachusetts Trying to be a doctor at the General Hospital. He notes a patient who observes a patient that covers a healthy ship to reconstruct blood flow around a blocked coronary artery. Surgeon, both patients are looking for the legs, arms, arms and finally, the stomach, suitable for use. “It was really really wild,” says Niklason. He realized that it had to be a better way.

Started with blood vessels growing in a laboratory from several cells gathered from pig vessels. When they moved them to the animal, they worked as a real thing.

It was a long way to a product approved by a FDA after early practices. Niklason and his team for more than a decade, for more than a decade, the human body and tissue areolated blood vascular cells. They tested the cells from more than 700 donors, and saw that those of five of these donors are most effective in the lab grow and expand. Niklason, Humacyte’s five donors, 500,000 and one million engineers have enough cells to make blood vessels, he said.

The company currently has a group of 200 gangs using a specially designed humiliating polymer, specially designed, specially designed, specially designed, with 6 millimeters thickness. Scales are placed in individual bags and are seeded with millions of donor cells. After that, the bags enter a school bus-sized incubator to soak in a food bath for two months. When the tissue grows, the structural support is secreting collagen and other proteins. Finally, the polymer melts the scaffolding and the cells are washed with a special solution. What is the “de-cell” flexible tissue in the form of blood vascular. The living human cell does not contain cells, it will not be rejected when implanting the patient.

“People are trying to get acquainted with a pipe outfit for a long time,” Anton Sidawy, the President of the American Surgeons College and George Washington University Medical Center related to the Vascular Surgeon Humacyte.