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Some medications could have the involuntary benefit of reducing the risk of dementia.
That is according to a recent study conducted by the universities of Cambridge and Exeter, where the researchers evaluated several existing drugs To see if they could do double service as dementia treatments.
The team reviewed data from 14 previous studies, which included more than 130 million patients and one million cases of dementia, according to a press release.
They determined that it was shown that several kinds of prescription medications affect the risk of dementia.
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The findings were published in Alzheimer’s and Dementia: translational research and clinical interventions.
The researchers determined that it was shown that several kinds of prescription medications affect the risk of dementia. (Istock)
“We urgently need new treatments to delay the progress of dementia, if not to avoid it,” said Co-First Author Dr. Ben Underwood, of the Department of Psychiatry of the University of Cambridge and Cambridgeshire and Peterborough Nhs Foundation Trust, in Liberar .
“If we can find drugs that already have a license for other conditions, then we can obtain them In tests And, crucially, you can make them available to patients a lot, much faster than we could do for a completely new medicine. “
Drugs that reduce and increase risk
Antibiotics, antivirals, anticoagulants (anticoagulants) and anticonvulsive (medications used to prevent or treat seizures) were linked to a reduced risk of dementia, according to the study.
Four vaccines – For hepatitis A, typhoid, hepatitis A and combined typhoid, and diphtheria, they were also associated with a reduced risk.
“If we can find medications that already have a license for other conditions, then we can put them in trials and, crucially, we can make them available to patients a lot, much faster than we could do for a completely new medicine.” (Istock)
“This finding supports the hypothesis that common dementias can be triggered by viral or by Bacterial infectionsand supports the recent interest in vaccines, such as the BCG vaccine for tuberculosis and decreased risk of dementia, “the researchers wrote in the statement.
It was also found that anti -inflammatory medications, such as ibuprofen, reduce the risk of dementia.
“Inflammation is increasingly considered as a significant taxsence to a wide range of diseases, and its role in dementia is backed by the fact that some genes that increase the risk of dementia are part of the inflammatory ways,” said the release.
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Some medications were associated with a higher risk of dementia, including Antipsychotic medications.
There was “conflicting evidence” for other drug classes, including those indicated for blood pressure, depression and diabetes.
“Although dementia lacks a cure and the available medications present challenges, my experience highlights the value of personalized care,” said a doctor (not in the photo) to Fox News Digital. (Istock)
Currently two medications are approved to Alzheimer’s treatment Yo.
Both are monoclonal antibodies that are administered through IV infusions. They work by reducing the accumulation of amyloid plaques in the brain, but they are only effective for those with an early stage and have the potential of some serious side effects, according to experts.
“You should never change your medication without discussing it first with your doctor.”
Dr. Chris Vercammen, internal medicine doctor certified by the Board at the University of California, San Francisco (UCSF), did not participate in the study, but shared his reaction to the findings.
“This review identifies medications classes that have an association with a higher risk of dementia,” Vercammen, which specializes in Geriatrics and palliative careFox News Digital said.
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“Systematic reviews offer the advantage of adding data in multiple studies, which can provide a more comprehensive understanding of the current state of knowledge on a topic.”
The study had some limitations, the researchers recognized, due to the differences in how each individual study was conducted and how the data was collected.
A doctor said that findings are “plausible” and highlight the importance of integral reviews of medicines for older adults at risk of dementia. (Istock)
Vecammen agreed that these types of revisions are limited by the general quality of the Available studies.
“In addition, unlike meta -analysis, they do not provide a summarized effect size for each medication, which makes it difficult to discuss the risk with precision.”
Despite the limitations, Vercammen said that the findings are “plausible” and highlight the importance of integral reviews of older adults at risk of dementia.
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Lourida emphasized that all medications have benefits and risks.
“You should never change your medicine without discussing it first With your doctorAnd you must talk to them if you have any concerns. “
Personalized attention implies “addressing the practical needs of the person who lives with dementia and their caregivers, the” second patients “, who provide essential daily support.” (Istock)
Vercammen agrees that patients who are considering new medications or treatments should consult with their doctors.
“Although dementia lacks a cure and the medications available have challenges, my experience highlights the value of Personalized care“He told Fox News Digital.
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“This implies addressing the practical needs of the person who lives with dementia and their caregivers, the” second patients “, who provide essential daily support. This is the essence of continuous and compassionate care in the absence of a cure.”
